Category Archives: usa

New cancer treatment with fewer side effects to be trialled in UK

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Up to 280 patients from seven countries will be recruited globally for the trial

Jane Kirby | Originally Published on The United Kingdom’s “Independent” Newspaper 2025

Saturday 06 December 2025 00:01 GMT

A groundbreaking trial for a prostate cancer treatment with fewer side effects has launched in the UK.

Backed by the Government-funded National Institute for Health and Care Research (NIHR), the trial will examine whether Aquablation – a therapy using robotics, AI and real-time imaging – works as well or better than traditional surgery, known as radical prostatectomy.

Radical prostatectomy involves removing the entire prostate gland in a bid to cure men of prostate cancer. The treatment is suitable for men whose cancer has not spread outside of the prostate gland or has spread to the area just outside the gland.

However, the operation carries a risk of serious side-effects, such as infection, erectile dysfunction and urinary problems.

Researchers hope Aquablation will minimise these issues.

The therapy is currently used in some centres to treat benign prostatic hyperplasia (BPH).

The treatment is suitable for men whose cancer has not spread outside of the prostate gland
The treatment is suitable for men whose cancer has not spread outside of the prostate gland (Getty/iStock)

Aquablation involves a robotic-assisted, high-pressure waterjet. Surgeons can also map the entire prostate in real time with ultrasound.

Using the technique, medics find cancerous tissue to remove while avoiding surrounding nerves and muscles associated with erectile function and the bladder.

The Royal Marsden NHS Foundation Trust in London is the first hospital in Europe to recruit a patient to the trial, which is being run in seven countries.

Overall, 280 patients will be recruited globally, all with early-stage, localised prostate cancer who have already decided to have surgery.

Philip Charlesworth, consultant urological surgeon at the Royal Marsden, said: “For men with prostate cancer confined to the prostate, curative options are excellent, however, we are becoming increasingly focused on the side-effects of the cancer treatment and how we can embrace new technology to maintain a man’s quality-of-life following their surgery.

“This trial is measuring Aquablation therapy, which uses a robotic approach to surgically remove the cancer, and to preserve a man’s ability to remain continent and maintain sexual activity.

“The potential for this trial is very exciting. It has an opportunity, depending on the results of the study, to add an alternative surgical treatment option for patients with localised prostate cancer across the globe.

“The ultimate aim, and my passion, is to improve prostate cancer treatments so that they cause less harm and are less invasive for the patient.

“I feel that this is an incredibly exciting prospect for the future of prostate cancer care.”

The Royal Marsden NHS Foundation Trust in London is the first hospital in Europe to recruit a patient to the trial
The Royal Marsden NHS Foundation Trust in London is the first hospital in Europe to recruit a patient to the trial (Getty)

Other potential treatments for localised prostate cancer include active surveillance or monitoring of the cancer and radiation.

The new trial is sponsored by the US company, Procept BioRobotics.

To date, there are more than 25 centres globally recruiting patients for the trial.

The four UK centres are the Royal Marsden, Guy’s and St Thomas’ NHS Foundation Trust, the Royal Free London NHS Foundation Trust and Norfolk and Norwich University Hospitals NHS Foundation Trust.

The trial comes after Health Secretary Wes Streeting said earlier this week he was “surprised” by the decision from scientific advisers to limit prostate cancer screening.

In a draft recommendation, the UK National Screening Committee (UKNSC), which advises the Government, said prostate cancer screening should not be made routinely available for the vast majority of men in the UK.

It said it would not recommend population screening using the prostate-specific antigen (PSA) test because it “is likely to cause more harm than good”.

Experts are expecting data within two years from a large trial launched by Prostate Cancer UK into whether combining PSA with other tests, such as rapid MRI scans, could lead to a recommendation for population-wide screening.

For now, the committee will put forward only a recommendation to screen men with BRCA1 and BRCA2 genetic mutations – which puts them at far higher risk of prostate cancer – every two years, between the ages of 45 and 61.

Main symptoms of prostate cancer

Prostate cancer usually starts to grow on the outer part of the prostate. If this happens, it can cause changes to the way you pee, such as:

  • finding it difficult to start peeing or straining to pee
  • having a weak flow of urine
  • “stop start” peeing
  • needing to pee urgently or often, or both
  • feeling like you still need to pee when you’ve just finished
  • peeing during the night

Other symptoms can include:

  • erectile dysfunction (being unable to get or keep an erection)
  • blood in your urine or blood in your semen
  • lower back pain and losing weight without trying to (these may be symptoms of advanced prostate cancer)

Speaking on Wednesday on BBC Breakfast, Mr Streeting said he was surprised by the decision.

He said: “I’m looking very carefully at why the national screening committee reached that decision.

“I’ve always said these things have got to be based on science and evidence, not on politics.

“But the recommendation did surprise me.

“This is contested. I’ve got people in the prostate cancer community and not just really prominent patients and celebrities and politicians who’ve used their experience and their voice in this debate, but among scientists and researchers.

“This is a draft recommendation. They consult on this for three months, and then we have to make a final decision.

“What I’m going to do is get some of those leading, best scientific voices and competing opinions around the table to thrash this out, to really interrogate the data and make sure that when I come on your programme having made a decision, it’s the right decision for the right reasons, the best evidence and the public can then understand why we’ve made the decision and the scientific community can understand why we’ve made the decision.

“But I am interrogating this data and recommendation because it did surprise me.”

Many experts argue that the PSA test is not very reliable because men with a high PSA level may not have cancer, and some men with cancer have a normal PSA result.

A positive test result may lead to unnecessary treatment for slow-growing or harmless tumours, leaving men at risk of side effects such as incontinence and erectile dysfunction.

But others argue that current evidence supports wider testing.

Homeless Prevention Program | BC Housing 2025

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Homeless Prevention Program

The Homeless Prevention Program provides portable rent supplements and support services to individuals in identified at-risk groups facing homelessness.

About the program

The Homeless Prevention Program is an initiative aimed at providing individuals in identified at-risk groups facing homelessness with portable rent supplements and support services to help them access rental housing in the private (non-subsidized) housing market.

The rent supplements and support services help recipients access rental housing in the private (non-subsidized) housing market and community-based services.

The Homeless Prevention Program operates, in many instances, as an enhancement to the existing Homeless Outreach Program / Indigenous Homeless Outreach Programs and targets individuals at transition points that put them at greater risk of homelessness.

Cost: None. Services are free.

Am I eligible?

To be eligible, you (or someone you know) are at immediate risk of homelessness. This includes:

  • Youth transitioning out of foster care
  • Women who have experienced violence or are at risk of violence
  • Individuals leaving the correctional or hospital systems
  • Individuals of Indigenous descent

Age

Services

If you are eligible and approved, the rent supplement can assist with:

  • Your rent
  • Your damage deposit
  • Costs that help you secure housing (for example, getting identification)
  • Transportation to a housing opportunity
  • Storage for your belongings as you wait to move into a new home
  • Ensuring access to utilities (for example, heat and water)
  • Moving expenses
  • Home start-up items

You cannot use the rent supplement for:

  • Rent, if you are already receiving a subsidy
  • Expenses not related to housing or this Program
  • Clinical health and treatment services
  • Medical or clinical staff expenses
  • Daycare expenses

Please contact an outreach worker for full details. An outreach worker will be able to determine what you are eligible for.

Who to contact

Contact a Homeless Prevention Program Service Provider or go to the nearest Emergency Shelter and ask to speak to staff.

Outreach staff will ask a few questions about your situation and income to determine your eligibility.

Note: Rental supplements are intended to be temporary.

Originally published on the British Columbia Housing Program website.

What the tiny little bugs in your carpet are, and why they could be bad news.

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Tom Kershaw & Paige Oldfield

Sun 16 February 2025 at 11:37 am GMT-8·1-min read

-Credit:Getty
-Credit:Getty

They may be small and swift, but if you notice this tiny silver creature scurrying around your home, you could be facing a significant and costly issue. Experts are advising anyone who spots a silverfish in their property to promptly check for dampness.

These shiny, teardrop-shaped insects thrive in moist conditions and are particularly fond of areas with water.

If you see one darting into or out of your skirting boards or crevices around window sills, it’s likely a sign of damp and moisture within your property. If not addressed, dampness can lead to a host of problems, including cracked bricks, rotting joists, decaying plaster, and spreading mould spores. In extreme cases, it can even compromise the structural integrity of the property and impact air quality.

Dampness can result from various factors, such as leaky drainpipes, condensation, ageing damp proofing, or inadequate ventilation, especially in bathrooms or kitchens where water vapour tends to linger. Identifying the cause can be tricky, but the presence of silverfish indoors usually signals that there’s dampness requiring attention.

Silverfish can be a sign of huge issues -Credit:Getty
Silverfish can be a sign of huge issues -Credit:Getty

The sooner signs of dampness are detected, the easier it will be to eradicate the bugs. It recommends looking for indications on walls like wet or damp patches, peeling wallpaper, and flaking plaster.

Other telltale signs include damp and musty smells, rotting wood, and the emergence of mould and mildew on walls, floors, or ceilings.

Among the proposed remedies are utilising a dehumidifier, maintaining good ventilation in your home, inspecting your gutters for leaks, applying damp-proof paint to your walls and, if necessary, engaging a professional to address areas impacted by rising dampness.

Originally published on Yahoo! United Kingdom

What Can I Do About A Slumlord?

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Dealing with a slumlord can be incredibly frustrating and stressful, but there are steps you can take to protect your rights and improve your living situation. Here’s a guide to help you navigate the situation:

1. Know Your Rights

  • Familiarize yourself with local tenant laws and housing codes. These vary by location but generally guarantee your right to a safe and habitable living environment.
  • Common landlord responsibilities include providing:
    • Working utilities (heat, water, electricity).
    • Proper sanitation and waste disposal.
    • Structural integrity (no leaks, mold, or pest infestations).
    • Safe and secure locks on doors and windows.
  • If your landlord is failing to meet these standards, they may be violating the law.

2. Document Everything

  • Keep a detailed record of all issues, including:
    • Photos and videos of unsafe or unsanitary conditions.
    • Written notes about when problems started and how they’ve been ignored.
    • Copies of all communication with your landlord (emails, texts, letters, etc.).
  • This documentation will be critical if you need to take legal action or report the landlord.

3. Communicate with Your Landlord

  • Notify your landlord in writing about the issues and request repairs. Be specific, polite, and keep a copy of the letter or email.
  • If they don’t respond or refuse to make repairs, send a follow-up notice and mention your legal rights.

4. Report Code Violations

  • Contact your local housing authority, health department, or building code enforcement agency to report unsafe or unsanitary conditions.
  • An inspector may visit your property and issue a violation notice to the landlord, forcing them to make repairs.
Pittsburgh, Pennsylvania, USA – Some abandoned townhouses standing in Uptown district

5. Withhold Rent or Repair and Deduct

  • In some areas, tenants are allowed to withhold rent or pay for repairs themselves and deduct the cost from rent. However, this can be risky, so:
    • Check your local laws to ensure this is allowed.
    • Notify your landlord in writing before taking action.
    • Keep receipts and documentation for all repairs.

6. Join or Organize with Other Tenants

  • If other tenants are experiencing similar issues, consider organizing as a group. Landlords are more likely to respond to collective action.
  • You can also reach out to local tenant unions or advocacy groups for support.

7. Seek Legal Help

  • If your landlord continues to neglect their responsibilities, consult a tenant attorney or legal aid organization.
  • You may be able to:
    • Sue for damages or compensation.
    • Break your lease without penalty.
    • Force the landlord to make repairs through a court order.

8. Consider Moving

  • If the situation doesn’t improve and your health or safety is at risk, it may be best to find a new place to live.
  • Before moving, ensure you’re not violating your lease and that you’ve followed proper legal procedures to protect yourself from retaliation or eviction.

9. Report to Local Media

  • If the situation is severe and widespread, contacting local news outlets can bring attention to the issue and pressure the landlord to act.

10. Stay Safe

  • If you feel threatened or unsafe due to your landlord’s actions, contact local law enforcement or a tenant advocacy group immediately.

Resources to Help You:

  • Local Housing Authority: For reporting code violations or unsafe conditions.
  • Legal Aid Organizations: For free or low-cost legal advice.
  • Tenant Unions: For advocacy and support in organizing with other tenants.
  • State or Local Tenant Rights Websites: For information on your specific rights.

By taking these steps, you can hold your landlord accountable and work toward a safer, healthier living environment.

Is There a Fundamental Logic to Life?

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 by Matt Williams

One of the more daunting questions related to astrobiology—the search for life in the cosmos—concerns the nature of life itself. For over a century, biologists have known that life on Earth comes down to the basic building blocks of DNA, RNA, and amino acids. What’s more, studies of the fossil record have shown that life has been subject to many evolutionary pathways leading to diverse organisms. At the same time, there is ample evidence that convergence and constraints play a strong role in limiting the types of evolutionary domains life can achieve.

For astrobiologists, this naturally raises questions about extraterrestrial life, which is currently constrained by our limited frame of reference. For instance, can scientists predict what life may be like on other planets based on what is known about life here on Earth? An international team led by researchers from the Santa Fe Institute (SFI) addressed these and other questions in a recent paper. After considering case studies across various fields, they conclude that certain fundamental limits prevent some life forms from existing.

The research team was led by Ricard Solé, the head of the ICREA-Complex Systems Lab at the Universitat Pompeu Fabra and an External Professor at the Santa Fe Institute (SFI). He was joined by multiple SFI colleagues and researchers from the Institute of Biology at the University of Graz, the Complex Multilayer Networks Lab, the Padua Center for Network Medicine (PCNM), Umeå University, the Massachusetts Institute of Technology (MIT), the Georgia Institute of Technology, the Tokyo Institute of Technology, and the European Centre for Living Technology (ECLT).

Artist’s impression of Earth during the Archean Eon. Credit: Smithsonian National Museum of Natural History

The team considered what an interstellar probe might find if it landed on an exoplanet and began looking for signs of life. How might such a mission recognize life that evolved in a biosphere different from what exists here on Earth? Assuming physical and chemical pre-conditions are required for life to emerge, the odds would likely be much greater. However, the issue becomes far more complex when one looks beyond evolutionary biology and astrobiology to consider synthetic biology and bioengineering.

According to Solé and his team, all of these considerations (taken together) come down to one question: can scientists predict what possible living forms of organization exist beyond what we know from Earth’s biosphere? Between not knowing what to look for and the challenge of synthetic biology, said Solé, this presents a major challenge for astrobiologists:

“The big issue is the detection of biosignatures. Detecting exoplanet atmospheres with the proper resolution is becoming a reality and will improve over the following decades. But how do we define a solid criterion to say that a measured chemical composition is connected to life? 

“[Synthetic biology] will be a parallel thread in this adventure. Synthetic life can provide profound clues on what to expect and how likely it is under given conditions. To us, synthetic biology is a powerful way to interrogate nature about the possible.”

The sequence where amino acids and peptides come together to form organic cells. Credit: peptidesciences.com

To investigate these fundamental questions, the team considered case studies from thermodynamics, computation, genetics, cellular development, brain science, ecology, and evolution. They also consider previous research attempting to model evolution based on convergent evolution (different species independently evolve similar traits or behaviors), natural selection, and the limits imposed by a biosphere. From this, said Solé, they identified certain requirements that all lifeforms exhibit:

“We have looked at the most fundamental level: the logic of life across sales, given several informational, physical, and chemical boundaries that seem to be inescapable. Cells as fundamental units, for example, seem to be an expected attractor in terms of structure: vesicles and micelles are automatically formed and allow for the emergence of discrete units.”

The authors also point to historical examples where people predicted some complex features of life that biologists later confirmed. A major example is Erwin Schrödinger’s 1944 book What is Life? in which he predicted that genetic material is an aperiodic crystal—a non-repeating structure that still has a precise arrangement—that encodes information that guides the development of an organism. This proposal inspired James Watson and Francis Crick to conduct research that would lead them to discover the structure of DNA in 1953.

However, said Solé, there is also the work of John von Neumann that was years ahead of the molecular biology revolution. He and his team refer to von Neumann’s “universal constructor” concept, a model for a self-replicating machine based on the logic of cellular life and reproduction. “Life could, in principle, adopt very diverse configurations, but we claim that all life forms will share some inevitable features, such as linear information polymers or the presence of parasites,” Solé summarized.

The first implementation of von Neumann’s self-reproducing universal constructor. Three generations of machines are shown: the second has nearly finished constructing the third. Credit: Wikimedia/Ferkel

In the meantime, he added, much needs to be done before astrobiology can confidently predict what forms life could take in our Universe:

“We propose a set of case studies that cover a broad range of life complexity properties. This provides a well-defined road map to developing the fundamentals. In some cases, such as the inevitability of parasites, the observation is enormously strong, and we have some intuitions about why this happens, but not yet a theoretical argument that is universal. Developing and proving these ideas will require novel connections among diverse fields, from computation and synthetic biology to ecology and evolution.”

The team’s paper, “Fundamental constraints to the logic of living systems,” appeared in Interface Focus (a Royal Society publication).

Further Reading: Santa Fe Institute, Interface Focus

Originally Published January 2nd, 2025 at Universe Today.

Authored by: Matt Williams

Saying No to Overtime

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For hourly workers, earning time and a half can sometimes be awesome and well worth the extra hours. But it can be less than great when you have plans or want to spend time with your family. Unfortunately, saying no to overtime is a bit difficult because of something called mandatory overtime.

What is Mandatory Overtime?

As defined by Business Management Daily, mandatory overtime is “the practice of requiring employees to work more than a standard 40-hour workweek.” Other words for it are forced or compulsory overtime. Although an employee may refuse to work mandatory overtime, it is completely legal for an employer to fire an employee that chooses to do so. Additionally, paystub generation is an essential component of accurate record-keeping and payroll management. Read this article to learn more.

The Fair Labor Standards act (FLSA) is the relevant law when it comes to mandatory overtime. Instead of prohibiting employees working over 40 hours a week, it states that all such extra hours are paid at one and a half the hourly rate. For those who are self employed, it’s crucial to manage their time and workload effectively to avoid burnout.

Employers like mandatory overtime for several reasons. They can use mandatory overtime as needed during busier times of the year without having to hire additional workers.

Saying No to Overtime

So, now that we know what mandatory overtime is, how could you say no when you have a conflict?

Make a Plan

Before you tell your boss, you can’t do overtime, plan out your answer. What’s your reason? Most managers can be understanding of conflicts like taking care of your kids or a loved one, or plans you already made well in advance. If you’re dealing with burnout and are concerned you won’t be able to do the work well without resting, hopefully your boss will understand that as well.

It’s also important to keep in mind how much overtime you’ve been saying no to lately. If this is a position where overtime is expected, you may need to pick your battles when it comes to asking to not work over 40 hours.

Talk to Your Boss

Now that you have a plan, it’s time to talk things over with your boss. Despite the name of this article, try not to actually say the word “no.” That can be seen as negative. You just want to explain to your boss what’s going on, and why you can’t take on extra hours now.

If They Say No

If your boss denies your request to not take on overtime, you might evaluate your current job. If you truly have a reason for not being able to do the overtime, it’s hopefully resolvable. It’s also possible that the position you’re in is just one that requires frequent overtime, and you aren’t currently a good fit for it.

My Name is Brad – A Docu-drama Film / Project in Memory of Kelly Thomas and Countless Others Who Fall Victim to the Stigma of Mental Health and Homelessness in America

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Bradley James was born on April 13th, 1972. Kelly Thomas was born on April 5th, 1974. While neither met each other, they both share something in common. They both suffered from schizophrenia. While Brad lives in British Columbia, struggling to make ends meet, Kelly was not that lucky. On July 10th, 2011, while many in America were glued to their television screens, watching in awe as the US team defeated Brazil during the semi-final of the 2011 FIFA Women’s World Cup, Kelly Thomas lay in a hospital bed, bloody and dying.

Kelly Thomas, a man who had struggled with fits of schizophrenia his entire life, was dragged out into the streets and brutally beaten by six officers of the Fullerton California police department – he later succumbed to his injuries.

Now, 57 Years of Soul Music Radio is collaborating with The Urban Survivor Humanitarian Network and Cheektowaga-Omni Media Marketing based in Vancouver, British Columbia, Canada, to tell Kelly’s story to the world. The company is raising funds via Slated, a crowdfunding platform for filmmakers, to launch the production of their film, “My Name Is Brad” in early Spring 2021.

This docudrama film is an initiative to recognize severe mental health issues and make them a mainstream topic of conversation. The film is aimed to show the controversy surrounding mental illnesses and police misconduct. It revolves around the lives of Brad James and Kelly Thomas.

With the current scenarios looking to get worse before they get better, the producers of “My Name Is Brad” believe that now’s the right time to bring this topic to the forefront of humanitarian initiatives that should be prioritized. With the new President in the Oval Office, we are closer to this dream than ever before – to end the injustice, indignation, and stigma associated with mental health and homelessness.

All funds raised through this film will be used to kick start an Urban housing development in all major cities. Modular container housing can be purchased for less than $2000 per unit. Since the government spends millions on everything else, it’s time to end homelessness and help those who are struck with mental illness.

From Homelessness to Renting: How to Find Rental Housing without References

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Homeless
The solace of silence is sometimes the only vocal support one gets without friends and family references.

There is no point in sugar-coating the fact that transitioning from homelessness to renting can be quite difficult for an individual, especially in cities like Toronto or Vancouver. From a landlord’s perspective, these markets are full of eligible and desirable tenants, so why would they lend their property to someone without any reference and an unstable (or non-existing) rental history.

This is a challenge most homeless people face, even when they have found a stable job and have enough money for a deposit. Finding rental housing without references can be tough but not impossible. There are a few things you can do:

1. Seek out your regional Housing First* program. It’s designed to help homeless people find stable homes. You’d need to contribute a portion of your income (ideally 30% or more) while the rest would be covered by rent subsidies. It also helps you establish a rent history that can open up more rental housing options for you.

2. Provide potential landlord proof of stable income. If you’ve been working for a while, bring your last three payslips and, preferably, a letter from your employer stating your good behavior (and that they don’t have any plans to let you go in the foreseeable future).

3. If you have a stable income and money for monthly rent but not the deposit, charities like Canadian Red Cross and Salvation Army might assist you (financially). With a decent deposit amount (say three-months rent), you might be able to convince potential landlords to rent to you, even if you don’t have references.

4. Don’t fake a reference history. It is a huge red flag, and if you get caught, it might disrupt your chances of renting with other landlords as well.

5. Talk to the people who are running emergency shelters. They might be able to guide you to individuals who might be inclined to rent to you without references, just to pull you out of homelessness. If not, they might be able to put you in touch with local housing assistance programs you might not be aware of.

Be honest, talk to the people helping homeless individuals in your community, try to save as much money as you can for rent and deposit, find a co-signer if you can, and make sure your employer puts in a good word for you.

*https://www.bchousing.org/projects-partners/funding-opportunities/RHFP

Boggles Brown – The Blurb

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-From “Boggles Brown – My Cartoon Life in the Land Of Schizophrenia” inner sleeve. – 2010

Boggles Brown is broke, except for the “People With Disabilities Allowance” he gets once a month. This month, he lives in a run-down motel – he manages to buy an old beat-up Toyota which is unreliable but reliable if you know what I mean. Somtimes he thinks his car may be bi-polar.

He wonders whether he should be using one of those fancy-named gasoline additives like “Engine-X,” I imagine “Engine-X” to be somewhat like Olanzapine, only for cars.

Boggles Brown struggled through college. He graduated,worked for a while and then became bonkers. It was not worth the ecstacy or all the raves in the world to lose his mind – he knows that now. But it is his life, what to do?

Boggles Brown is not how I see myself so much, as how I think others see me. My mom has read some of my cartoons and scratched her head. I imagine a lot of people will do the same. But that’s not the point – is it? Am I Canada’s Andy Warhol? I think not.

I hope you like Boggles, and if you don’t, I hope you keep it to yourself because the point is that it gave me something to do.

These are all hand-drawn on whatever paper I could find.

– Boggles Brown; “BJAF” 2010

“Genes” – Boggles Brown; Urban Survival Media 2009

Exclusive Boggles Brown T-Shirts Online

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Browse and bedazzle when you wear the words of our talkative transient.

Greetings Readers,

Now, like never before, we have been waiting for a marketing breakthrough to gain that glimmer of interactivity on it’s way to your wardrobe. This time, we hired Social Media Management Company UK to help us in our branding and marketing our new product. It’s here – Boggles Brown multi-colour T-Shirts where you get to write the dialogue for our lovable but lunatic street-sage.

https://www.slated.com/films/736655

Drop by and donate to give the My Name Is Brad docudrama the funding it needs and order a Boggles Brown exclusive hand drawn T-Shirt by local artist Brad James.

Stay Safe and Think of B. Brown When You’re Feeling Down.

– The Crew At The Urban Survivor and My Name Is Brad